Reference control for high-sensitivity c-reactive protein...

Details Reference control for high-sensitivity c-reactive protein... Reference control for high-sensitivity c-reactive protein...

G - Physics

01

N

G01N 33/68 (2006.01) C07K 1/16 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2456829

Low-concentration reference controls for C-reactive protein assays are prepared from higher-level starting materials by simple filtration using silica-type filter media formerly used for removing lipids. This process avoids the need for antibodies to capture the protein and resuspend it. Surprisingly, the removal of CRP by the silica-type filter media is selective toward CRP, having little or negligible effect on other proteins in the starting matrix, and accordingly little or negligible change in the total protein content.

Selon l'invention, on prépare des témoins de référence à faible concentration destinés à des dosages de protéine C-réactive à partir de matières de départ de niveau supérieur par simple filtration au moyen de milieux filtrants de type silice préalablement utilisés pour extraire des lipides. Cette méthode permet de supprimer la nécessité pour les anticorps de capturer la protéine et de la resuspendre. Etonnamment, l'extraction de la protéine CRP au moyen de ces milieux filtrants de type silice est sélective envers la protéine CRP et exerce un effet réduit ou négligeable sur les autres protéines dans la matrice de départ, d'où un changement réduit ou négligeable de la teneur en protéines totale.

Affiliated with

Also associated with

Rating

Reference control for high-sensitivity c-reactive protein... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reference control for high-sensitivity c-reactive protein..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reference control for high-sensitivity c-reactive protein... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1880861