Refolding transforming growth factor beta family proteins

Details Refolding transforming growth factor beta family proteins Refolding transforming growth factor beta family proteins

A - Human Necessities

61

K

A61K 47/42 (2006.01) A61K 47/02 (2006.01) A61K 47/18 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2577690

Compositions and methods for folding proteins belonging to the transforming growth factor beta superfamily are disclosed. The compositions and methods allow for the folding of such proteins when produced in an expression system that does not yield a properly folded, biologically active product.

L'invention concerne des compositions et des procédés pour le repliement de protéines appartenant à la superfamille du facteur de croissance transformant bêta. Les compositions et procédés de l'invention permettent d'assurer le repliement desdites protéines lorsque ces dernières sont produites dans un système d'expression ne produisant pas de produit actif sur le plan biologique correctement replié.

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