A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/38 (2006.01) C12N 5/077 (2010.01) A61F 2/02 (2006.01) A61L 27/40 (2006.01) C12N 11/02 (2006.01)
Patent
CA 2744559
A graft containing a scaffold that includes a matrix in which are positioned mesenchymal progenitor cells (MPCs) has the capacity to substantially improve wound healing, including wounds resulting from injury to nerve, bone and vascular tissue. MPCs can be harvested from debrided muscle tissue following orthopaedic trauma. The traumatized muscle- derived progenitor cells are a readily available autologous cell source that can be utilized to effect or improve wound healing in a variety of therapeutic settings and vehicles.
L'invention porte sur une greffe comprenant un échafaudage comprenant une matrice dans laquelle sont positionnées les cellules progénitrices mésenchymateuses (MPC). Il s'agit d'une greffe ayant la capacité d'améliorer de façon substantielle la guérison d'une lésion, y compris des lésions résultant d'une blessure à un tissu nerveux, osseux et vasculaire. Les MPCs peuvent être récoltées à partir de tissu musculaire débridé à la suite d'un traumatisme orthopédique. Les cellules progénitrices issues d'un muscle traumatisé constituent une source de cellules autologues faciles à obtenir, qui peuvent être utilisées pour réaliser ou améliorer la guérison d'une lésion dans une diversité de paramètres et de véhicules thérapeutiques.
Jackson Wesley M.
Nesti Leon J.
Tuan Rocky S.
The Henry M. Jackson Foundation For The Advancement Of Military Inc.
The United States Government As Represented By The National Institutes Of Health Office Of Te
The United States Government As Represented By The Secretary Of The Arm Y.
Torys Llp
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