C - Chemistry – Metallurgy – 08 – B
Patent
C - Chemistry, Metallurgy
08
B
C08B 37/16 (2006.01)
Patent
CA 2047726
A process for preparing regiospecifically hydroxyalkylated .alpha.-,.beta.- or .gamma.-cyclodextrins wherein the substitution is either directed toward hydroxyls 2 or 2,3 of the glucose units with little substitution on hydroxyl 6 or toward hydroxyls 6 and with little substitution on the secondary hydroxyls. The regiospecificity is obtained through the proper control of basicity of the reaction mixtures which are comprised of epoxide and cyclodextrins and a suitable solvent.
L'invention concerne un procédé de préparation de cyclodextrines alpha, beta ou gamma hydroxyalcoylées spécifiquement par région, dans lequel la substitution concerne soit des hydroxyles 2 ou 2,3 des unités de glucose, avec peu de substitution sur l'hydroxyle 6, soit des hydroxyles 6 avec peu de substitution dans les hydroxyles secondaires. On obtient la spécificité par région en réglant correctement la basicité des mélanges de réaction, composés d'époxyde ainsi que de cyclodextrines et d'un solvant adapté.
Lindberg Bengt
Pitha Josef
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica Naamloze Vennootschap
LandOfFree
Regioselective substitutions in cyclodextrins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Regioselective substitutions in cyclodextrins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Regioselective substitutions in cyclodextrins will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1493067