Regioselective synthesis of rapamycin derivatives

Details Regioselective synthesis of rapamycin derivatives Regioselective synthesis of rapamycin derivatives

C - Chemistry, Metallurgy

07

F

C07F 7/18 (2006.01) C07D 498/18 (2006.01)

Patent

CA 2385461

This invention provides a regioselective process for preparing a 42-ester or ether of rapamycin, and 31-silyl ether intermediates.

L'invention concerne un procédé stéréosélectif servant à préparer un 42-ester ou éther de rapamycine, ainsi que des intermédiaires de 31-silyle éther.

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