Regiospecific process for the preparation of...

Details Regiospecific process for the preparation of... Regiospecific process for the preparation of...

C - Chemistry, Metallurgy

07

D

C07D 249/08 (2006.01)

Patent

CA 2515181

A regiospecific process for the preparation of 4-[1-(4-cyanophenyl)-1-(1,2,4- triazol-1-yl)methyl]benzonitrile comprising reacting 4-halomethylbenzonitrile with 4-amino-1,2,4-triazole followed by deamination and reaction with 4- fluorobenzonitrile.

Cette invention se rapporte à un procédé régiospécifique servant à la préparation de 4-[1-(4-cyanophényl)-1-(1,2,4-triazol-1-yl)méthyl]benzonitrile et consistant à cet effet à faire réagir du 4-halométhylbenzonitrile avec du 4-amino-1,2,4-triazole, puis à effectuer une désamination et une réaction avec du 4-fluorobenzonitrile.

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