Regiospecific synthesis of nicotine derivatives

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 7/10 (2006.01)

Patent

CA 2546260

Methods of synthesizing nicotine analogs and derivatives are described. The methods are particularly useful for the regioselective production of enantiomerically pure nicotine analogs having substituents at the C4 position. Intermediates useful for the synthesis of such compounds are also described.

L'invention concerne des procédés de synthèse d'analogues et de dérivés de nicotine. Ces procédés sont particulièrement utiles dans la production régiosélective d'analogues de nicotine énantiomériquement pures comprenant des substituants dans la position C4. Des intermédiaires utiles pour la synthèse de ces composés sont également décrits.

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