C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) A01H 5/00 (2006.01) A01K 67/027 (2006.01) A61K 31/56 (2006.01) A61K 31/65 (2006.01) A61K 38/13 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 14/725 (2006.01) C07K 19/00 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01)
Patent
CA 2167282
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
On a développé un processus général de dimérisation ou d'oligomérisation régulée (pouvant être induite) de protéines intracellulaires. Des procédés et des substances sont décrites, lesquels permettent d'amorcer de manière régulable l'apoptose (mort cellulaire programmée) dans des cellules produites par technique génétique.
Belshaw Peter
Crabtree Gerald R.
Schreiber Stuart L.
Spencer David M.
Wandless Thomas J.
Osler Hoskin & Harcourt Llp
President And Fellows Of Harvard College
The Board Of Trustees Of The Leland Stanford Junior University
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