Regulated genes by stimulation of chondrocytes with il-1.beta.

Details Regulated genes by stimulation of chondrocytes with il-1.beta. Regulated genes by stimulation of chondrocytes with il-1.beta.

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) A61K 38/39 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) C07H 21/04 (2006.01) C12N 15/09 (2006.01) C12N 15/12 (2006.01) C12N 15/16 (2006.01) G01N 33/564 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2159957

The present invention refers to the novel use of osteopontin, calnexin and TSG-6gene product in the diagnosis, prophylaxis or therapy of IL-1.beta. mediated diseases of connective tissues and to novel genes induced or repressed by stimulation of chondrocytes with IL-1.beta. and their use in the diagnosis, prophylaxis or therapy of IL- 1.beta. mediated diseases of connective tissues.

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