C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/56 (2006.01) A01H 1/00 (2006.01) C12N 9/24 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2288672
The invention lies in the field of regulation of carbon flow in the metabolism of the cell. It has been found that induction of a change in the intracellular availability of the saccharide trehalose-6-phosphate (T-6-P) induces modifications of the development and/or composition of cells, tissue and organs in vivo. These changes can be induced by inhibiting the endogenous enzyme trehalase which is capable of hydrolysing trehalose into two glucose moieties.
L'invention a trait au domaine de la régulation du débit de carbone dans le métabolisme d'une cellule. On a trouvé que l'induction d'un changement dans la disponibilité intracellulaire du tréhalose-6-phosphate saccharidique (T-6-P) provoquait in vivo des modifications de développement et/ou de composition de cellules, tissus et organes. Ces changements peuvent être induits par inhibition de l'enzyme endogène tréhalase, laquelle est capable d'hydrolyser le tréhalose en deux fractions glucosiques.
Goddijn Oscar Johannes Maria
Pen Jan
Smeekens Josephus Christianus Maria
Smits Maria Theresia
Gowling Lafleur Henderson Llp
Mogen International N.v.
Syngenta Mogen B.v.
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