Regulation of cellproliferation and differentiation using...

A - Human Necessities – 61 – K

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A61K 38/29 (2006.01) A61K 8/14 (2006.01) A61K 8/64 (2006.01) A61K 9/127 (2006.01) A61Q 7/00 (2006.01) A61Q 7/02 (2006.01) A61Q 19/00 (2006.01) C07K 14/575 (2006.01) C07K 14/635 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2413860

Methods are disclosed for the regulation of cell differentiation and proliferation, e.g., for treating hyperproliferative skin disorder, such as psoriasis, for enhancing wound healing, for stimulation hair growth and inhibiting hair growth, by topical administration of parathyroid hormone (PTH), parathyroid related peptide (PTHrP), or fragment, analog or derivative thereof, and salts thereof, encapsulated by particular liposomes.

Cette invention concerne des méthodes de régulation de la différentiation et de la prolifération cellulaires s'utilisant notamment pour traiter des troubles cutanés hyperproliferatifs tels que le psoriasis, pour accélérer une cicatrisation, pour stimuler ou pour ralentir la croissance des cheveux, ceci grâce à l'administration topique d'une parathormone (PTH), d'un peptide en rapport avec la parathyroïde (PTHrP), ou bien d'un fragment, d'un analogue ou d'un dérivé ou de sels des substances précitées, encapsulés par des liposomes particuliers.

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