Regulation of guanine nucleotide exchange factor

Details Regulation of guanine nucleotide exchange factor Regulation of guanine nucleotide exchange factor

A - Human Necessities

61

K

A61K 31/122 (2006.01) A61K 31/404 (2006.01) A61K 31/4184 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/18 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2533074

The invention relates generally to the methods of treating brain diseases and compounds for treating brain diseases, and more specifically relates to using compounds that are able to modulate guanine nucleotide exchange factors for proteins belonging to the Rap family of small GTPases to treat diseases of the brain, such as Alzheimer's and Schizophrenia.

L'invention concerne généralement des procédés de traitement de maladies cérébrales, des composés pour le traitement de maladies cérébrales, et plus spécifiquement l'utilisation de composés pour moduler les facteurs d'échange du nucléotide guanine pour les protéines appartenant à la famille Rap des petites GTPases, pour le traitement de maladies cérébrales, telles que la maladie d'Alzheimer et la schizophrénie.

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