Regulation of plant fertility by modulation of gaba levels...

A - Human Necessities – 01 – N

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A01N 33/08 (2006.01) A01H 1/00 (2006.01) A01H 1/02 (2006.01) A01N 37/44 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2451727

The invention provides methods for the alteration of fertility in plants through modulation of floral GABA levels. The techniques of the invention may find use in plant breeding techniques. Also provided by the invention are assays for the screening of candidate modulators of GABA metabolism or GABA analogs through the identification of affects on fertility following application of the candidate modulator to a plant. The technique provides an alternative to animal testing and is amenable to large scale application.

L'invention concerne des procédés de modification de fertilité dans des végétaux, par le biais de la modulation de niveaux de GABA floraux. Ces procédés peuvent être utilisés dans des procédés de sélection végétale. L'invention concerne également des épreuves biologiques pour le criblage de modulateurs candidats de métabolisme du GABA ou d'analogues du GABA, par le biais de l'identification d'effets sur la fertilité, se produisant suite à l'application du modulateur candidat sur un végétal. Ce procédé constitue une alternative à l'expérimentation sur les animaux, et peut s'adapter à des applications de grande échelle.

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