Regulation of the growth hormone/igf-1 axis

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/02 (2006.01) A61K 45/00 (2006.01) C12Q 1/00 (2006.01) G01N 33/567 (2006.01) G01N 33/68 (2006.01) G01N 33/74 (2006.01)

Patent

CA 2497826

This disclosure provides, inter alia, treatments and compositions that alter life span regulation and cellular responses to diseases and disorders by antagonizing the GH/1IGF-1 axis. Also provided are methods of screening for agents that can modulate the GH/IGF-1 axis.

L'invention concerne, entre autres, des traitements et des compositions permettant de modifier la régulation de la durée de vie et les réponses cellulaires à des maladies et des troubles par antagonisation de l'axe GH/IGF-1. L'invention concerne également des méthodes de criblage d'agents pouvant moduler l'axe GH/IGF-1.

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