Regulator of notch signaling activity

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2349477

The invention relates to a novel regulator protein termed Notchless, and to nucleic acid that encodes this protein. The invention also relates to methods of diagnosis and therapy of certain diseases, particularly cancer and neurodegenerative diseases, using this protein and its encoding nucleic acids.

L'invention concerne une nouvelle protéine régulatrice dénommée Notchless et l'acide nucléique codant pour ladite protéine; ainsi que des méthodes permettant de diagnostiquer et de traiter certaines maladies, notamment le cancer et les maladies neurodégénératives, au moyen de ladite protéine et des acides nucléiques qui la codent.

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