Regulators of mmp-9 and uses therof

Details Regulators of mmp-9 and uses therof Regulators of mmp-9 and uses therof

C - Chemistry, Metallurgy

07

K

C07K 16/40 (2006.01) A61K 39/395 (2006.01) C12Q 1/37 (2006.01) C12N 9/64 (2006.01)

Patent

CA 2695969

A method of regulating an activity of metalloproteinase 9(MMP-9) is disclosed. The method comprises contacting the MMP-9 with an agent which specifically interacts with an OG domain of the MMP-9. Molecules capable of specifically interacting with the OG domain, methods of identifying same, pharmaceutical compositions comprising same and uses thereof are also disclosed.

La présente invention concerne un procédé de régulation d'une activité de la métalloprotéinase 9 (MMP-9). Le procédé comprend la mise en contact de la MMP-9 avec un agent qui interagit spécifiquement avec un domaine OG de la MMP-9. L'invention concerne également des molécules capables d'interagir spécifiquement avec le domaine OG, des procédés pour les identifier, des compositions pharmaceutiques les comprenant et leurs utilisations.

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