Regulators of ucp2 gene expression

Details Regulators of ucp2 gene expression Regulators of ucp2 gene expression

C - Chemistry, Metallurgy

12

N

C12N 1/00 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2286894

The invention relates to regulators of UCP2 gene transcription, including novel UCP2 transcriptional promoters. UCP2 gene promoters are used in diagnosis and pharmaceutical development. In particular, transfected cells comprising UCP2 gene promoters operably linked to a reporter are used in high- throughput pharmaceutical screens.

L'invention concerne des régulateurs de la transcription du gène d'UCP2, dont des nouveaux promoteurs de transcription d'UCP2. Lesdits promoteurs du gène d'UCP2 sont utilisés dans la recherche pharmaceutique et le diagnostic. Des cellules transfectées comprenant des promoteurs du gène d'UCP2 liés activement à un reporter, sont notamment utilisées dans les criblages pharmacologiques.

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