Regulators of ucp3 gene expression

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C12N 1/00 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2303844

The invention relates to regulators of UCP3 gene transcription, including novel UCP3 transcriptional regulators. UCP3 gene promoters are used in diagnosis and pharmaceutical development. In particular, transfected cells comprising UCP3 gene promoters operably linked to a reporter are used in high- throughput pharmaceutical screens.

L'invention concerne des régulateurs de la transcription du gène UCP3, y compris de nouveaux régulateurs transcriptionnels du gène UCP3. Les promoteurs du gène UCP3 sont utilisés dans des procédés diagnostiques et pharmaceutiques. En particulier, des cellules transfectées, comprenant des promoteurs du gène UCP3 fonctionnellement liés à un marqueur, sont utilisés dans des cribles pharmaceutiques à haut rendement.

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