Regulatory zinc finger proteins

Details Regulatory zinc finger proteins Regulatory zinc finger proteins

C - Chemistry, Metallurgy

12

N

C12N 15/29 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2508631

Disclosed are chimeric zinc finger proteins that can regulate endogenous genes. Examples of such proteins include proteins that can regulate VEGF-A expression. The proteins and nucleic acid encoding them can be used to modulate angiogenesis.

La présente invention a trait à des protéines à doigt de zinc chimériques aptes à la régulation de gènes endogènes. Des exemples de telles protéines comprennent des protéines aptes à la régulation de l'expression du facteur de croissance endothélial vasculaire A (VEGF-A). Les protéines et les acides nucléiques codant pour ces protéines peuvent être utilisés pour la modulation de l'angiogenèse.

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