Rehydratable antacid composition

Details Rehydratable antacid composition Rehydratable antacid composition

A - Human Necessities

61

K

167/124

A61K 33/08 (2006.01) A61K 9/00 (2006.01) A61K 9/14 (2006.01)

Patent

CA 1259919

A B S T R A C T An rehydratable antacid composition of magaldrate gel and a process for preparing same are described by the invention. The composition is prepared from and contains precipitated and undried magaldrate gel, a polyhydric alcohol and fluidizing amounts of a first and second fluidizer. One fluidizer is provided by an aluminum hydroxide gel having colloidal properties and the second by a pharmaceutically acceptable citrate ion source including citric acid. The process and composition are characterized in providing rehydratable antacid composition which when admixed with water forms a fluid, resuspendible, pharmaceutically elegant suspension possessing high antacid capacity and stability at even elevated magaldrate concentrations in addition to the ability to fluidize stiff, paste-like magaldrate gel cakes.

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