Rejuvenation compositions and methods for their use

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/00 (2006.01) A61K 8/60 (2006.01) A61K 31/70 (2006.01) A61Q 19/08 (2006.01) C12N 5/06 (2006.01) C12N 9/08 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) A61K 7/48 (1990.01)

Patent

CA 2080336

2080336 9115226 PCTABS00007 This invention provides a method for restoring the proliferative potential of senescent cells by decreasing the concentration of intranuclear interleukin-I. This invention also provides antisense oligonucleotides that, when added to senescent cell cultures, restore the proliferative potential of these cells. This invention, thus, provides means and methods for rejuvenating cells.

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