C - Chemistry – Metallurgy – 08 – G
Patent
C - Chemistry, Metallurgy
08
G
C08G 65/333 (2006.01) A61K 47/34 (2006.01) C08G 65/335 (2006.01) C08K 5/31 (2006.01) C08L 71/02 (2006.01) C12N 15/88 (2006.01) C12N 15/113 (2010.01)
Patent
CA 2742838
The present invention relates to polymer conjugated releasable lipids and nanoparticle compositions containing the same for the delivery of nucleic acids and methods of modulating gene expression using the same. In particular, this invention relates to releasable polymeric lipids containing an acid-labile linker based on a ketal or acetal-containing linker, or an imine-containing linker.
La présente invention concerne des lipides libérables conjugués à un polymère et des compositions nanoparticulaires contenant ces lipides pour la délivrance d'acides nucléiques, ainsi que des procédés de modulation de l'expression génique basés sur ces lipides. En particulier, cette invention concerne des lipides-polymères libérables contenant un lieur labile en milieu acide basé sur un lieur contenant un cétal ou un acétal, ou un lieur contenant une imine.
Shi Lianjun
Wu Dechun
Yan Weili
Zhao Hong
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Enzon Pharmaceuticals Inc.
LandOfFree
Releasable polymeric lipids for nucleic acids delivery systems does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Releasable polymeric lipids for nucleic acids delivery systems, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Releasable polymeric lipids for nucleic acids delivery systems will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1542196