G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/82 (2006.01)
Patent
CA 2624129
The present invention concerns a reagent composition for releasing vitamin D compounds bound to vitamin D-binding protein, a method for the detection of a 25-hydroxyvitamin D compound in which the 25-hydroxyvitamin D compound is released from vitamin D-binding protein using this reagent and the mixture obtained in this manner is analysed, the use of the reagent to release vitamin D compounds as well as a kit for detecting 25-hydroxyvitamin D which contains the reagent for releasing vitamin D compounds in addition to the usual immunological reagents.
La présente invention concerne une composition réactive pour la libération de composés de vitamine D liés à la protéine liant la vitamine D ainsi qu~un procédé de détection d~un composé de 25-hydroxyvitamine D. Dans ce procédé, le composé 25-hydroxyvitamine D est libéré à partir de la protéine liant la vitamine D en utilisant ce réactif et le mélange ainsi obtenu est analysé. L~invention concerne également l~utilisation du réactif visant à libérer des composés de vitamine D ainsi qu~un kit de détection de la 25-hydroxyvitamine D qui contient, outre les réactifs immunologiques habituels, le réactif de libération de composés de vitamine D.
Feldmann Susanne
Horn Nicole
Huber Erasmus
Kobold Uwe
Kyriatsoulis Apostolos
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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