Remedies for hepatitis

Details Remedies for hepatitis Remedies for hepatitis

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 38/08 (2006.01) A61K 38/17 (2006.01) A61K 38/39 (2006.01) A61K 45/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2252629

Remedies for hepatitis which contain integrin inhibitors as the active ingredient. The integrin inhibitors are exemplified by antibodies, proteins other than the antibodies, polypeptides, peptides, nucleic acids, saccharides and derivatives thereof and low molecular weight compounds originating therein, each capable of binding to integrins. Among all, anti-VLA-4 antibody, VLA-4 inhibiting peptides and low molecular weight VLA-4 inhibiting compounds are efficacious as remedies for hepatitis.

Remèdes pour l'hépatite, qui renferment des inhibiteurs d'intégrine comme ingrédients actifs. Les inhibiteurs de l'intégrine de l'invention sont des anticorps, des protéines autres que des anticorps, des polypeptides, des peptides, des acides nucléiques, des saccharides et des dérivés de ceux-ci, ainsi que des composés de faible poids moléculaire qui en sont issus, tous aptes à se lier aux intégrines. Parmi tous ces inhibiteurs, les anticorps anti-VLA-4, les peptides inhibiteurs de VLA-4 et les composés de faible poids moléculaire inhibiteurs de VLA-4 représentent tous des remèdes efficaces contre l'hépatite.

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