C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2746334
The present invention refers to the use of FasL antagonists, e.g. of humanized antibodies directed against human Fas ligands (also named CD95L or Apo1L and hereinafter abbreviated as FasL) for the prevention and/or treatment of skin diseases associated with keratinocytes acantholysis, particularly for the prevention and/or treatment of pemphigus.
La présente invention concerne l'utilisation d'antagonistes de FasL, par exemple d'anticorps humanisés dirigés contre les ligands Fas humains, que l'on appelle aussi CD95L ou Apo1L, et que l'on regroupe ici sous l'abréviation "FasL", cette utilisation étant destinée à la prévention et/ou au traitement de maladies de la peau associées à l'acantholyse des kératinocytes, et en particulier la prévention et/ou le traitement du pemphigus.
Marconi Alessandra
Pincelli Carlo
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Pincell Srl
LandOfFree
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