Removal method of granulocytes from blood and granulocyte...

A - Human Necessities – 61 – M

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167/114, 182/15.

A61M 1/36 (2006.01) A61K 35/14 (2006.01)

Patent

CA 1322718

ABSTRACT OF THE DISCLOSURE Granulocytes can be removed from blood by bringing the blood into contact with a carrier having higher affinity to granulocytes than to lymphocytes. The carrier is preferably a substance having a contact angle in a range of 55°-95° to water, e.g., polystyrene, cellulose acetate, nylon, polytrifluoro- ethylene or polyethylene terephthalate. A granulocyte removing apparatus is also disclosed. It comprises a granulocyte-adsorbing portion enclosing therein a carrier having higher affinity to granulocytes than to lymphocytes, a blood inflow port for causing blood to flow into the adsorbing portion, and a blood outflow port for allowing the blood, which has flowed in the adsorbing portion, to flow out of the adsorbing portion.

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