Removal of prion infectivity

Details Removal of prion infectivity Removal of prion infectivity

A - Human Necessities

61

L

A61L 2/00 (2006.01) A61L 2/18 (2006.01)

Patent

CA 2488502

Prion infectivity adsorbed onto substrates (for example, chromatographic columns used to fractionate blood plasma) is removed by treatment with 2M sodium chloride. Optionally, the substrate is further washed with 0.1M sodium hydroxide.

L'invention concerne l'élimination de l'infectiosité aux prions adsorbée sur des substrats (par exemple, colonnes de chromatographie utilisées pour fractionner le plasma sanguin), qui consiste à traiter un substrat au chlorure de sodium (2M), et ensuite éventuellement à laver le substrat à l'hydroxyde de sodium (0,1M).

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