Removal of viruses from protein solutions by ultrafiltration

Details Removal of viruses from protein solutions by ultrafiltration Removal of viruses from protein solutions by ultrafiltration

C - Chemistry, Metallurgy

12

N

C12N 7/02 (2006.01) A61L 2/02 (2006.01) B01D 61/14 (2006.01) C07K 1/34 (2006.01)

Patent

CA 2169122

The invention relates to the removal of viruses from aqueous solutions, as a rule protein solutions, by ultrafiltration. This entails the viruses to be removed being increased in size by incubation with a high molecu- lar weight receptor binding thereto, preferably a speci- fic antibody, so that, on the one hand, the separation effect is improved and, on the other hand, a larger pore diameter which can now be chosen for the filters used also makes it possible for smaller viruses to be separa- ted from larger protein molecules present in protein solutions, and, where appropriate, the filtration rate is increased.

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