Remyelination using neural stem cells

Details Remyelination using neural stem cells Remyelination using neural stem cells

A - Human Necessities

61

K

A61K 35/30 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 38/44 (2006.01) C07K 14/47 (2006.01) C07K 14/475 (2006.01) C07K 14/82 (2006.01) C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 9/08 (2006.01) C12N 9/38 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C12N 5/08 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2147162

A method for the remyelination of neurons is disclosed wherein neural stem cells isolated from adult or fetal neural tissue are proliferated in a culture medium containing a growth factor to produce precursor cells having a nestin (+) phenotype. The precursor cells are capable of differentiation into oligodendrocytes which, when associated with a demyelinated neuron, effect remyelination.

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