Renal function analysis method and apparatus

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01) A61B 5/00 (2006.01) A61B 5/20 (2006.01)

Patent

CA 2721846

A method for measuring a glomerular filtration rate in a mammalian kidney comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the blood stream of a mammalian subject. Over a pe-riod of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to de-termine the health of the subject's kidney. This method measures volume of plasma distribution based on a fluorescence of a mark-er molecule relative to a fluorescence of a reporter molecule.

Linvention concerne un procédé de mesure dun taux de filtration glomérulaire dans un rein mammalien, qui comprend une source de molécules rapporteuses et de molécules marqueuses fluorescentes. Les molécules fluorescentes sont introduites dans le courant sanguin dun sujet mammalien. Une mesure des intensités des molécules rapporteuses et des molécules marqueuses fluorescentes est réalisée pendant une certaine durée. Un taux est calculé pour déterminer la santé du rein du sujet. Ce procédé mesure la distribution du volume de plasma en fonction dune fluorescence dune molécule marqueuse par rapport à une fluorescence dune molécule rapporteuse.

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