Renin-inhibiting peptides

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/02 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07D 339/00 (2006.01) C07D 339/06 (2006.01) C07D 339/08 (2006.01) C07D 409/06 (2006.01) C07D 409/12 (2006.01) C07K 5/02 (2006.01) C07K 5/027 (2006.01) C07K 5/065 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2018458

A B S T R A C T Renin-inhibiting peptides of the formula Image (I) in which R1 is H, alkoxycarbonyl, benzyloxycarbonyl, morpholinocarbonyl, amino, or the like, B is a direct bond, proline or an amino acid radical, R2 is aryl, w is 0 or 1, A is -CH2- or -CH2-CH2 D and E each independently is a direct bond or amino acid radical, and X is OH, benzyloxy, alkoxy, an amino radical or Image and physiologically acceptable salts thereof. Le A 26 914

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