Renin inhibiting polypeptide analogs and intermediates

Details Renin inhibiting polypeptide analogs and intermediates Renin inhibiting polypeptide analogs and intermediates

C - Chemistry, Metallurgy

07

K

530/7.06

C07K 7/06 (2006.01) C07D 213/40 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01) C07K 5/10 (2006.01)

Patent

CA 1293840

ABSTRACT The present invention provides novel renin inhibitory peptides of the formula X-A-B-C-D-E-F-C-H-Z wherein E-F is a dihalo-substituted statine group, X and Z are terminal groups, and the remaining variables are absent or amino acid residues. These compounds are useful for administration to humans to treat hypertension.

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