C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 217/54 (2006.01) A61K 31/137 (2006.01) A61K 31/16 (2006.01) A61K 31/21 (2006.01) A61K 31/277 (2006.01) A61K 31/44 (2006.01) C07C 233/00 (2006.01) C07C 237/00 (2006.01) C07C 255/00 (2006.01) C07C 271/00 (2006.01) C07D 213/04 (2006.01)
Patent
CA 2696689
The present invention relates to biphenyl compounds of formula (I). These compounds are renin inhibitors of a non- peptidic nature and of low molecular weight. The invention further relates to a pharmaceutical composition containing said compounds, as well as their use and method of treatment of cardiovascular events and renal insufficiency.
La présente invention porte sur des composés biphénylés représentés par la formule (I). Ces composés sont des inhibiteurs de la rénine d'une nature non peptidique et d'une faible masse moléculaire. L'invention porte en outre sur une composition pharmaceutique contenant lesdits composés, ainsi que sur leur utilisation et sur un procédé de traitement d'événements cardiovasculaires et d'insuffisance rénale.
Aspiotis Renee
Dube Daniel
Fortin Rejean
Gallant Michel
Juteau Helene
Merck Frosst Canada Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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