C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/20 (2006.01) C07C 317/10 (2006.01) C07D 211/40 (2006.01) C07D 215/12 (2006.01) C07D 215/14 (2006.01) C07D 401/06 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2615048
The present invention relates to novel renin inhibitors of the general Formula (I), and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds. These novel renin inhibitors are used in treating cardiovascular events and renal insufficiency.
La présente invention concerne de nouveaux inhibiteurs de la rénine de formule générale (I) ainsi que leur utilisation comme ingrédients actifs dans la préparation de compositions pharmaceutiques. L'invention concerne également des aspects associés, y compris des procédés de préparation de ces composés. Ces nouveaux inhibiteurs de la rénine sont utilisés pour traiter des événements cardiovasculaires ainsi que l'insuffisance rénale.
Bayly Christopher I.
Chen Austin C.
Dube Daniel
Dube Laurence
Gallant Michel
Merck Frosst Canada Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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