Renin inhibitors

Details Renin inhibitors Renin inhibitors

C - Chemistry, Metallurgy

07

D

C07D 211/42 (2006.01) A61K 31/445 (2006.01) A61P 9/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2370888

The present invention relates to compound of formula (I) wherein R1, R2 and R3 are as defined in the description and claims and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment of diseases which are associated restenosis, glaucoma, cardiac infarct, high blood pressure and end organ damage, e.g. cardiac insufficiency and kidney insufficiency.

Cette invention se rapporte à un composé représenté par la formule (I), où R<1>, R<2> et R<3> sont définis dans les pièces descriptives et les revendications de la demande, ainsi qu'à des sels de ce composé acceptables sur le plan pharmaceutique. Ces composés servent à traiter les maladies associées à la resténose, le glaucome, les infarctus cardiaques, l'hypertension et les dommages aux organes terminaux, tels que l'insuffisance cardiaque et l'insuffisance rhénale.

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