Renin inhibitors

C - Chemistry – Metallurgy – 07 – K

Patent

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530/5, 167/103.0

C07K 5/027 (2006.01) C07C 229/34 (2006.01) C07C 271/22 (2006.01) C07C 311/19 (2006.01) C07D 207/08 (2006.01) C07D 209/48 (2006.01) C07D 233/54 (2006.01) C07D 263/26 (2006.01) C07K 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2022692

ABSTRACT Renin-inhibiting peptides of the formula Image (I) in which X represents a group of the formula Image or Image or represents hydroxyl, alkoxy having up to 8 carbon atoms, benzyloxy or a group of the formula -NR4R5, A, B, D and E are identical or different and in each case - represent a direct bond, - represent a radical of the formula Image in which Z - denotes oxygen, sulphur or the methylene group - represents a grouping of the formula Image or Image m - represents a number 0, 1 or 2, and L - represents a group of the formula -CH2-NR2R3 and physiologically acceptable salts thereof.

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