Renin inhibitors

Details Renin inhibitors Renin inhibitors

C - Chemistry, Metallurgy

07

F

C07F 9/655 (2006.01) A61K 31/66 (2006.01) A61K 38/05 (2006.01) C07D 307/52 (2006.01) C07F 9/6553 (2006.01) C07K 5/06 (2006.01) C07K 9/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2050434

31,287-00 RENIN INHIBITORS ABSTRACT Renin inhibiting compounds containing a single .alpha.-amino acid of the formula: Image wherein R1 is a phosphorus containing moiety, W is oxygen or NR3 and A is moiety selected from those of the formula: Image ; wherein Z is O, S, SO, SO2 and p is an integer from 1 to 2; and, when W is oxygen, R1 may be hydrogen and A may also be a moiety of the formula Image ; Image and analogs thereof which compounds inhibit the substrate-cleaving action of renin, pharmaceutical compositions containing these compounds, processes for producing the compounds and methods of treating hypertension which employ the novel renin inhibitors.

Affiliated with

Also associated with

Rating

Renin inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Renin inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Renin inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1738459