Renin inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 413/12 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 211/46 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01) C07D 451/06 (2006.01) C07D 451/14 (2006.01) C07D 498/08 (2006.01) C07D 513/08 (2006.01)

Patent

CA 2089268

2089268 9203429 PCTABS00010 A renin inhibiting compound of formula (I), wherein X is O, NH or S and G is a mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof; with the proviso that the compound is not N-(3-(4-Morpholino)propyl)-5(S)-(2(S)-(1(S)-(4-(methoxymethoxy)piperidin-1-yl_ )carbonyl-2-phenyl)ethoxyhexanamido)-6-cyclohexyl-4(S)-hydroxy-2(S)-isop ropylhexanamide.

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