Replicating or semi-replicating viral constructs,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01) C12N 15/00 (2006.01) C12N 15/867 (2006.01)

Patent

CA 2307933

The invention relates to the use of replicating or semi-replicating viral construct(s) for the preparation of a composition for gene delivery into cells in vivo, ex vivo or in vitro. The invention also relates to novel retroviral constructs, packaging cells and nucleic acids which can be used in methods of delivering polynucleotides to cells.

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