Replication-competent molecular clones of porcine endogenous...

Details Replication-competent molecular clones of porcine endogenous... Replication-competent molecular clones of porcine endogenous...

C - Chemistry, Metallurgy

12

N

C12N 15/48 (2006.01) A61K 39/21 (2006.01) C07K 14/15 (2006.01) C12N 7/00 (2006.01) C12N 15/10 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2438385

The present invention relates to functional, replication-competent full-length proviral PERV-A and PERV-B clones isolated directly from the pig genome, i.e. "native" PERV and allows the comparison of proviral PERV sequences from different origins on the molecular, structural and cellular level.

La présente invention concerne des clones du rétrovirus endogène porcin PERV-A et PERV-B, proviraux, entiers, compétents en réplication, isolés directement du génome porcin, c'est-à-dire du PERV natif, et la méthode de cette invention permet de comparer des séquences provirales PERV d'origines différentes au niveau moléculaire, structurel et cellulaire.

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