Replication competent viruses capable of silencing virus...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/861 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2562830

Described is a replication competent virus, being capable to replicate and having lytic capacity in tarjet cells, the virus comprising in the genome thereof, at least one DNA sequence coding for a silencing factor functional in reducing expression of a target gene in the said target cells, operably linked to one or more expression control sequences, funcional in the said target cells, and the use thereof in the preparation of a medicament and to the use thereof in a method for lysing target cells expressing a virus inhibitory factor.

L'invention concerne un virus compétent pour la réplication, pouvant assurer une réplication et présentant une capacité lytique dans des cellules cibles. Ledit virus comprend dans son génome au moins une séquence ADN codant pour un facteur d'atténuation qui permet de réduire l'expression d'un gène cible dans lesdites cellules cibles, ladite séquence étant fonctionnellement liée à une ou à plusieurs séquences de régulation d'expression, et étant fonctionnelle dans lesdites cellules cibles. L'invention concerne également l'utilisation dudit virus dans la préparation d'un médicament et son utilisation dans un procédé de lyse de cellules cibles exprimant un facteur d'inhibition de virus.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Replication competent viruses capable of silencing virus... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Replication competent viruses capable of silencing virus..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Replication competent viruses capable of silencing virus... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1495959

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.