Replicative rna-based amplification/detection system

Details Replicative rna-based amplification/detection system Replicative rna-based amplification/detection system

C - Chemistry, Metallurgy

12

Q

195/1.12, 150/8.

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 1339991

This invention relates to the use of functional reporter molecules in the detection and measurement of nucleic acid sequences in a sample, as a determination, for example, of pathogenic disease existence or potential. The invention is predicated on the utilization of a transcription step between the production of an appropriate reporter molecule and replication based amplification in order to increase the number of detectable species as an indirect reference to target nucleic acid sequence.

610547

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