Reporter-selectable hepatitis c virus replicon

Details Reporter-selectable hepatitis c virus replicon Reporter-selectable hepatitis c virus replicon

C - Chemistry, Metallurgy

12

N

C12N 15/51 (2006.01) C07K 14/09 (2006.01) C07K 14/18 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 7/00 (2006.01) C12N 15/86 (2006.01) C12Q 1/66 (2006.01)

Patent

CA 2483513

The invention relates to a reporter-selectable hepatitis C virus (HCV) replicon, and use of the replicon to generate stable, human hepatoma cell lines. The replicon and cell lines are useful in the compound screening process in HCV drug discovery.

L'invention concerne un réplicon de virus de l'hépatite C (VHC) sélectionnable par le rapporteur ainsi que l'utilisation du réplicon pour générer des lignées cellulaires stables d'hépatome humain. Le réplicon et les lignées cellulaires sont utilisées dans le procédé de criblage de composés par la recherche d'un médicament contre le VHC.

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