Resolution of mefloquine with o,o-di-p-aroyltartaric acid

Details Resolution of mefloquine with o,o-di-p-aroyltartaric acid Resolution of mefloquine with o,o-di-p-aroyltartaric acid

C - Chemistry, Metallurgy

07

D

C07D 215/14 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2503146

A process for increasing the optical purity of a mixture of enantiomers of mefloquine, used a substantially single enantiomer of a O, O-di-p- aroyltartaric acid as a resolving agent.

L'invention concerne un procédé permettant d'augmenter la pureté optique d'un mélange d'énantiomères de mefloquine. Ce procédé fait appel à un énantiomère sensiblement unique d'un acide O, O-di-p-aroyltartarique, en tant qu'agent de résolution.

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