C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 265/32 (2006.01)
Patent
CA 2543580
Disclosed is a method for preparing (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5- trimethyl-2-morpholinol and pharmaceutically acceptable salts such as the (+)- (2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol hydrochloride salt via dynamic kinetic resolution.
L'invention concerne un procédé destiné à préparer du (+)-(2S,3S)-2-(3-chlorophényl)-3,5,5-triméthyl-2-morpholinol et des sels pharmaceutiquement acceptables tels que l'hydrochlorure de (+)-(2S,3S)-2-(3-chlorophényl)-3,5,5-triméthyl-2-morpholinol par résolution cinétique dynamique.
Harris Michael Anthony
Negus Alan
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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