Resorbable pharmaceutical formulation for the continuous...

A - Human Necessities – 61 – L

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A61L 15/42 (2006.01) A61K 38/48 (2006.01) A61L 15/32 (2006.01) C12N 9/74 (2006.01)

Patent

CA 2485268

The invention relates to resorbable pharmaceutical formulations for the continuous local release of thrombin. The thrombin is embedded in resorbable polymer spheres which are incorporated in a collagen sponge. The inventive formulation provides a resorbable haemostatic for using in surgery, especially dental surgery, in dentoalveolar operations.

La présente invention concerne des formulations pharmaceutiques résorbables destinées à la libération continue locale de thrombine. La thrombine est enrobée dans des sphères en polymère résorbable, les sphères étant incorporées dans une éponge de collagène. La formulation selon l'invention propose un hémostyptique résorbable destiné à être utilisé en chirurgie, notamment en chirurgie dentaire dans le cas d'interventions dento-alvéolaires.

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