Restless legs syndrome/periodic appendicular dyskinesia...

A - Human Necessities – 01 – K

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A01K 67/027 (2006.01)

Patent

CA 2567429

A model animal for restless legs syndrome/periodic appendicular dyskinesia. As a result of administration to the abdominal cavity of mouse of a plasma component of peripheral blood collected from renal failure patients judged as suffering restless legs syndrome/periodic appendicular dyskinesia, it has been found that the mouse strikingly exhibits behavior peculiar to these diseases and hence can be used as a disease model mouse. This model animal can be used in identifying of the causative agent of restless legs syndrome/periodic appendicular dyskinesia and in development and evaluation of any methods of diagnosis and treatment for these diseases.

Un animal modèle pour la dyskinésie appendiculaire périodique/le syndrome des jambes sans repos. Suite à l'administration dans la cavité abdominale d'une souris d'un composant de plasma de sang périphérique collecté à partir de patients souffrant d'insuffisance rénale considérés comme ayant le syndrome des jambes sans repos/de dyskinésie appendiculaire périodique, il a été découvert que la souris montre de manière étonnante un comportement étrange à ces maladies et peut donc être utilisée comme une souris modèle de la maladie. Cet animal modèle peut servir à identifier l'agent causal du syndrome des jambes sans repos/de la dyskinésie appendiculaire et dans le développement et l'évaluation de toutes méthodes de diagnostic et de traitement de ces maladies.

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