G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) H01J 49/04 (2006.01) G01N 30/90 (2006.01) G01N 30/95 (2006.01)
Patent
CA 2294417
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by desorption spectrometry. The methods are useful in biology and medecine, including clinical diagnostics and drug discovery.
L'invention concerne des procédés de chromatographie sur produit retenu destinés à séparer des analytes dans un échantillon. Ces procédés consistent tout d'abord à adsorber lesdits analytes sur un substrat, dans des conditions de sélectivité variable, puis à détecter les analytes accumulés sur ce substrat par spectrométrie de désorption. Ces procédés sont utiles en biologie et en médecine, notamment pour des diagnostics cliniques et la recherche de médicaments.
Hutchens T. William
Yip Tai-Tung
Ciphergen Biosystems Inc
Smart & Biggar
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