Retentate chromatography and protein chip arrays with...

G - Physics – 01 – N

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Details

G01N 30/00 (2006.01) B01D 15/38 (2006.01) B01J 20/286 (2006.01) B01J 20/32 (2006.01) G01N 30/90 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) H01J 49/04 (2006.01) G01N 30/95 (2006.01) H01J 49/16 (2006.01)

Patent

CA 2294040

This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectively conditions, and detecting the analytes retained on the substrate by desorption spectrometry. The methods are useful in biology and medicine, including clinical diagnostics and drug discovery.

Procédé de chromatographie par rétentat permettant de détecter des analytes dans un échantillon. Lesdits procédés consistent à adsorber les analytes sur un substrat dans une pluralité de conditions de sélectivité différentes, et à détecter les analytes retenus sur le substrat par spectrométrie de désorption. Lesdits procédés sont utiles en biologie et en médecine, par exemple pour des diagnostics cliniques et la découverte de médicaments.

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