C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/08 (2006.01) A61F 2/14 (2006.01) A61K 35/44 (2006.01) A61L 27/00 (2006.01) C12N 5/02 (2006.01) C12N 11/02 (2006.01)
Patent
CA 2161659
An implant is provided for transplantation to the subretinal area of a host eye comprising a laminate of a monolayer of retinal pigment epithelium (RPE) cells and a non-tonic, flexible support that, upon exposure to a set of predetermined conditions, will not impede normal eye tissue function. A method for preparing a population of RPE cells for transplantation to the subretinal acre of a host eye is also provided. The method includes the steps of providing donor tissue comprising RPE cells, harvesting from that tissue RPE cells, and apposing the harvested RPE cells as a monolayer to a non-toxic flexible support that, upon transplantation to the subretinal area and exposure to a set of predetermined conditions will not impede normal eye tissue function of the hit eye and the transplanted population. A method for transplanting the above implant is also provided, comprising providing the implant, making an incision through a host's eye, at least partially detaching the retina to permit access to the subretinal area, and positioning the implant in the accessed area.
Borden Ladner Gervais Llp
Photogenesis Incorporated
LandOfFree
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